{"id":389,"date":"2026-04-06T17:42:30","date_gmt":"2026-04-06T15:42:30","guid":{"rendered":"https:\/\/erlaxatu.fr\/index.php\/q-ppr-horton\/"},"modified":"2026-04-06T17:42:30","modified_gmt":"2026-04-06T15:42:30","slug":"q-ppr-horton","status":"publish","type":"page","link":"https:\/\/erlaxatu.fr\/index.php\/q-ppr-horton\/","title":{"rendered":"Q. PPR &#038;  Horton"},"content":{"rendered":"\n<style>\n.fc {\n  border: 2px solid #ddd;\n  border-radius: 12px;\n  padding: 18px;\n  margin: 14px 0;\n  background: #fff;\n  cursor: pointer;\n  user-select: none;\n}\n\n.fc .fc-q, .fc .fc-a { display: none; }\n\n.fc[data-state=\"q\"] .fc-q { display: block; }\n.fc[data-state=\"a\"] .fc-a { display: block; }\n\n.fc:focus { outline: 3px solid rgba(0,0,0,0.15); }\n.fc .fc-label { font-weight: 700; }\n\n\/* no-JS (details\/summary) *\/\n.fc.fc-details { cursor: default; }\n.fc.fc-details summary { list-style: none; cursor: pointer; }\n.fc.fc-details summary::-webkit-details-marker { display: none; }\n.fc.fc-details .fc-a { display: none; margin-top: 8px; }\n.fc.fc-details[open] .fc-a { display: block; }\n<\/style>\n\n<div class=\"fc\" data-state=\"q\" tabindex=\"0\" role=\"button\" aria-pressed=\"false\">\n  <div class=\"fc-q\">\n    <span class=\"fc-label\">Question :<\/span><br>\n    \u00c0 partir de quel \u00e2ge \u00e9voque-t-on une PPR ou une ACG ???\n  <\/div>\n  <div class=\"fc-a\">\n    <span class=\"fc-label\">R\u00e9ponse :<\/span><br>\n    Apr\u00e8s 50 ans, avec un pic entre 70 et 80 ans. Les formes plus jeunes sont tr\u00e8s rares.\n  <\/div>\n<\/div>\n\n<div class=\"fc\" data-state=\"q\" tabindex=\"0\" role=\"button\" aria-pressed=\"false\">\n  <div class=\"fc-q\">\n    <span class=\"fc-label\">Question :<\/span><br>\n    Quelle est la fr\u00e9quence relative de la PPR par rapport \u00e0 l\u2019ACG ??\n  <\/div>\n  <div class=\"fc-a\">\n    <span class=\"fc-label\">R\u00e9ponse :<\/span><br>\n    La PPR est environ 3 \u00e0 10 fois plus fr\u00e9quente que l\u2019ACG.\n  <\/div>\n<\/div>\n\n<div class=\"fc\" data-state=\"q\" tabindex=\"0\" role=\"button\" aria-pressed=\"false\">\n  <div class=\"fc-q\">\n    <span class=\"fc-label\">Question :<\/span><br>\n    Quel est le sexe le plus touch\u00e9 par la PPR et l\u2019ACG ?\n  <\/div>\n  <div class=\"fc-a\">\n    <span class=\"fc-label\">R\u00e9ponse :<\/span><br>\n    Les femmes (sex-ratio environ 2 femmes pour 1 homme).\n  <\/div>\n<\/div>\n\n<div class=\"fc\" data-state=\"q\" tabindex=\"0\" role=\"button\" aria-pressed=\"false\">\n  <div class=\"fc-q\">\n    <span class=\"fc-label\">Question :<\/span><br>\n    Quels sont les sympt\u00f4mes cl\u00e9s de la PPR ?\n  <\/div>\n  <div class=\"fc-a\">\n    <span class=\"fc-label\">R\u00e9ponse :<\/span><br>\n    Douleurs et raideur inflammatoire des ceintures scapulaire et pelvienne, surtout matinale.\n  <\/div>\n<\/div>\n\n<div class=\"fc\" data-state=\"q\" tabindex=\"0\" role=\"button\" aria-pressed=\"false\">\n  <div class=\"fc-q\">\n    <span class=\"fc-label\">Question :<\/span><br>\n    Quel signe biologique est quasi constant dans la PPR ?\n  <\/div>\n  <div class=\"fc-a\">\n    <span class=\"fc-label\">R\u00e9ponse :<\/span><br>\n    Syndrome inflammatoire (CRP et\/ou VS \u00e9lev\u00e9es), mais au moins 10 % sans sd inflammatoire biologique\n  <\/div>\n<\/div>\n\n<div class=\"fc\" data-state=\"q\" tabindex=\"0\" role=\"button\" aria-pressed=\"false\">\n  <div class=\"fc-q\">\n    <span class=\"fc-label\">Question :<\/span><br>\n    Quel. s examen.s d\u2019imagerie est utile dans la PPR ?\n  <\/div>\n  <div class=\"fc-a\">\n    <span class=\"fc-label\">R\u00e9ponse :<\/span><br>\n    \u00c9chographie des \u00e9paules\/bassin montrant des bursites souvent bilat\u00e9rales. TEP montre fixations caract\u00e9ristiques\n  <\/div>\n<\/div>\n\n<div class=\"fc\" data-state=\"q\" tabindex=\"0\" role=\"button\" aria-pressed=\"false\">\n  <div class=\"fc-q\">\n    <span class=\"fc-label\">Question :<\/span><br>\n    Quel traitement est de r\u00e9f\u00e9rence dans la PPR ?\n  <\/div>\n  <div class=\"fc-a\">\n    <span class=\"fc-label\">R\u00e9ponse :<\/span><br>\n    Prednisone par voie orale.\n  <\/div>\n<\/div>\n\n<div class=\"fc\" data-state=\"q\" tabindex=\"0\" role=\"button\" aria-pressed=\"false\">\n  <div class=\"fc-q\">\n    <span class=\"fc-label\">Question :<\/span><br>\n    Quelle est la dose habituelle initiale de prednisone dans la PPR ?\n  <\/div>\n  <div class=\"fc-a\">\n    <span class=\"fc-label\">R\u00e9ponse :<\/span><br>\n    Environ 15 mg\/j (12,5 \u00e0 30 mg\/j selon le contexte, 0,3 mg\/kg)\n  <\/div>\n<\/div>\n\n<div class=\"fc\" data-state=\"q\" tabindex=\"0\" role=\"button\" aria-pressed=\"false\">\n  <div class=\"fc-q\">\n    <span class=\"fc-label\">Question :<\/span><br>\n    Quel argument th\u00e9rapeutique est souvent utilis\u00e9 pour conforter le diagnostic de PPR ?\n  <\/div>\n  <div class=\"fc-a\">\n    <span class=\"fc-label\">R\u00e9ponse :<\/span><br>\n    R\u00e9ponse rapide et spectaculaire aux cortico\u00efdes en 24\u201372 h.\n  <\/div>\n<\/div>\n\n<div class=\"fc\" data-state=\"q\" tabindex=\"0\" role=\"button\" aria-pressed=\"false\">\n  <div class=\"fc-q\">\n    <span class=\"fc-label\">Question :<\/span><br>\n    Quelle est la dur\u00e9e moyenne du traitement de la PPR ?\n  <\/div>\n  <div class=\"fc-a\">\n    <span class=\"fc-label\">R\u00e9ponse :<\/span><br>\n    Environ 12 \u00e0 24 mois avec d\u00e9croissance progressive.\n  <\/div>\n<\/div>\n\n<div class=\"fc\" data-state=\"q\" tabindex=\"0\" role=\"button\" aria-pressed=\"false\">\n  <div class=\"fc-q\">\n    <span class=\"fc-label\">Question :<\/span><br>\n    Qu\u2019est-ce que l\u2019art\u00e9rite \u00e0 cellules g\u00e9antes (Horton) ?\n  <\/div>\n  <div class=\"fc-a\">\n    <span class=\"fc-label\">R\u00e9ponse :<\/span><br>\n    Une vascularite des art\u00e8res de moyen et gros calibre, surtout les branches de la carotide externe.\n  <\/div>\n<\/div>\n\n<div class=\"fc\" data-state=\"q\" tabindex=\"0\" role=\"button\" aria-pressed=\"false\">\n  <div class=\"fc-q\">\n    <span class=\"fc-label\">Question :<\/span><br>\n    Quel sympt\u00f4me fonctionnel est tr\u00e8s \u00e9vocateur de l\u2019ACG ?\n  <\/div>\n  <div class=\"fc-a\">\n    <span class=\"fc-label\">R\u00e9ponse :<\/span><br>\n    La claudication de la m\u00e2choire \u00e0 la mastication.\n  <\/div>\n<\/div>\n\n<div class=\"fc\" data-state=\"q\" tabindex=\"0\" role=\"button\" aria-pressed=\"false\">\n  <div class=\"fc-q\">\n    <span class=\"fc-label\">Question :<\/span><br>\n    Quel est le principal risque \u00e9volutif de l\u2019ACG ?\n  <\/div>\n  <div class=\"fc-a\">\n    <span class=\"fc-label\">R\u00e9ponse :<\/span><br>\n    La c\u00e9cit\u00e9 isch\u00e9mique brutale.\n  <\/div>\n<\/div>\n\n<div class=\"fc\" data-state=\"q\" tabindex=\"0\" role=\"button\" aria-pressed=\"false\">\n  <div class=\"fc-q\">\n    <span class=\"fc-label\">Question :<\/span><br>\n    Quel signe ophtalmologique impose une urgence th\u00e9rapeutique ?\n  <\/div>\n  <div class=\"fc-a\">\n    <span class=\"fc-label\">R\u00e9ponse :<\/span><br>\n    Baisse brutale indolore de l\u2019acuit\u00e9 visuelle ou amaurose.\n  <\/div>\n<\/div>\n\n<div class=\"fc\" data-state=\"q\" tabindex=\"0\" role=\"button\" aria-pressed=\"false\">\n  <div class=\"fc-q\">\n    <span class=\"fc-label\">Question :<\/span><br>\n    Quel examen histologique confirme le diagnostic d\u2019ACG ?\n  <\/div>\n  <div class=\"fc-a\">\n    <span class=\"fc-label\">R\u00e9ponse :<\/span><br>\n    La biopsie de l\u2019art\u00e8re temporale.\n  <\/div>\n<\/div>\n\n<div class=\"fc\" data-state=\"q\" tabindex=\"0\" role=\"button\" aria-pressed=\"false\">\n  <div class=\"fc-q\">\n    <span class=\"fc-label\">Question :<\/span><br>\n    La biopsie temporale doit-elle retarder le traitement ?\n  <\/div>\n  <div class=\"fc-a\">\n    <span class=\"fc-label\">R\u00e9ponse :<\/span><br>\n    Non, le traitement cortico\u00efde ne doit jamais \u00eatre retard\u00e9.\n  <\/div>\n<\/div>\n\n<div class=\"fc\" data-state=\"q\" tabindex=\"0\" role=\"button\" aria-pressed=\"false\">\n  <div class=\"fc-q\">\n    <span class=\"fc-label\">Question :<\/span><br>\n    Quel est l\u2019examen de r\u00e9f\u00e9rence pour les formes extracr\u00e2niennes d\u2019ACG ?\n  <\/div>\n  <div class=\"fc-a\">\n    <span class=\"fc-label\">R\u00e9ponse :<\/span><br>\n    Le TEP-scan.\n  <\/div>\n<\/div>\n\n<div class=\"fc\" data-state=\"q\" tabindex=\"0\" role=\"button\" aria-pressed=\"false\">\n  <div class=\"fc-q\">\n    <span class=\"fc-label\">Question :<\/span><br>\n    Quelle est la dose initiale de cortico\u00efdes dans l\u2019ACG sans atteinte oculaire ?\n  <\/div>\n  <div class=\"fc-a\">\n    <span class=\"fc-label\">R\u00e9ponse :<\/span><br>\n    Environ 0,7 mg\/kg\/j de prednisone.\n  <\/div>\n<\/div>\n\n<div class=\"fc\" data-state=\"q\" tabindex=\"0\" role=\"button\" aria-pressed=\"false\">\n  <div class=\"fc-q\">\n    <span class=\"fc-label\">Question :<\/span><br>\n    Quelle est la dose recommand\u00e9e en cas de signes oculaires ou isch\u00e9miques ?\n  <\/div>\n  <div class=\"fc-a\">\n    <span class=\"fc-label\">R\u00e9ponse :<\/span><br>\n    Environ 1 mg\/kg\/j de prednisone (\u00b1 bolus IV).\n  <\/div>\n<\/div>\n\n<div class=\"fc\" data-state=\"q\" tabindex=\"0\" role=\"button\" aria-pressed=\"false\">\n  <div class=\"fc-q\">\n    <span class=\"fc-label\">Question :<\/span><br>\n    Quel traitement d\u2019\u00e9pargne cortisonique a une AMM dans l\u2019ACG ?\n  <\/div>\n  <div class=\"fc-a\">\n    <span class=\"fc-label\">R\u00e9ponse :<\/span><br>\n    Le tocilizumab (anti-IL6).\n  <\/div>\n<\/div>\n\n<script>\n(function () {\n  function toggle(card) {\n    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R\u00e9ponse : Apr\u00e8s 50 ans, avec [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"footnotes":""},"class_list":["post-389","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/erlaxatu.fr\/index.php\/wp-json\/wp\/v2\/pages\/389","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/erlaxatu.fr\/index.php\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/erlaxatu.fr\/index.php\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/erlaxatu.fr\/index.php\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/erlaxatu.fr\/index.php\/wp-json\/wp\/v2\/comments?post=389"}],"version-history":[{"count":0,"href":"https:\/\/erlaxatu.fr\/index.php\/wp-json\/wp\/v2\/pages\/389\/revisions"}],"wp:attachment":[{"href":"https:\/\/erlaxatu.fr\/index.php\/wp-json\/wp\/v2\/media?parent=389"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}